Leo Sher, M.D. Our research paper, “Lower CSF homovanillic acid levels in depressed patients with a history of alcoholism” was published 20 years ago, in the September 2003 issue of Neuropsychopharmacology (1). We compared clinical features and cerebrospinal fluid (CSF) monoamine metabolites in depressed subjects with or without a history of alcoholism and healthy volunteers. […]
Rana Anwar, M.D., Steven Lippmann, M.D. Introduction: Genetic testing for Huntington’s Disease (HD) offers a precise diagnosis but raises many questions. These include privacy concerns to complex family dynamics; the impact of HD testing extends beyond individual choices. There are clinical dilemmas surrounding HD genetic testing that require thoughtful consideration. Discrimination /Privacy: One of the […]
Amrit Kahlon, M.D., Adil Khan, M.D., Steven Lippmann, M.D. […]
Leo Sher, M.D. Our research work, “Antisuicidal effect of lithium in bipolar patients: Is there an age-specific effect?” has been published in the Journal of Affective Disorders online ahead of print (1). The age-related antisuicidal effect of lithium and valproate was compared in ninety-four (n = 94) high-risk bipolar suicide attempters. Individuals with bipolar disorder […]
Leo Sher, M.D. Three days ago, U.S. Centers for Disease Control and Prevention (CDC) released provisional data on suicide rates in the U.S. in 2022 (1). More people died by suicide in the U.S. in 2022 than any other year on record. Overall, 49,449 Americans (39,255 men and 10,194 women) died by suicide in 2022, […]
Steven Lippmann, M.D. There are concerns nation-wide about not having the latest interventional psychiatric treatment options available for clinical prescribing. For just one single example, intranasal esketamine is not uniformly present in some healthcare formularies. There are instances where financial, clinical, and/or other administrative hurdles block this new pharmacotherapy even to hospital emergency medicine departments. […]
Leo Sher, M.D. A research report, “Obesity as pleiotropic risk state for metabolic and mental health throughout life” has recently been published in Translational Psychiatry (1). A significant part of the worldwide population is overweight. Obesity is a substantial global health burden. The prevalence rates of obesity have been progressively increasing over the past decades. […]
Steven Lippmann, M.D. I bet that most of you have never heard of kratom. Well, it is an opioid type of drug widely available in this country with little restriction … yes, surprising ! Already used by millions of people, its widening distribution is again in the news recently as a public health hazard and […]
Leo Sher, M.D. Our research work, “Dehydroepiandrosterone and dehydroepiandrosterone sulfate levels in combat veterans with or without a history of suicide attempt” was published 5 years ago, in the July 2018 issue of Acta Psychiatrica Scandinavica (1). Demographic and clinical parameters of combat veterans who have made a suicide attempt postdeployment and combat veterans who […]
Leo Sher, M.D. Our research work, “Depressed patients with co-occurring alcohol use disorders: a unique patient population” was published 15 years ago, in the June 2008 issue of the Journal of Clinical Psychiatry (1). We compared depressed patients with or without comorbid alcohol use disorder with respect to demographic and clinical parameters. 505 individuals were […]
