L. Daws1; N. L. Baganz Strode1; J. L. Munn1; J. M. Boyce-Rustay2; A. Holmes2 1. Physiology, UTHSCSA, San Antonio, TX, USA. 2. Behavioral Science and Genetics, NIAAA, Bethesda, MD, USA. The serotonin (5-HT) transporter (SERT; 5-HTT) provides the primary mechanism for terminating 5-HT neurotransmission and there is evidence that it is under regulatory control of […]
D. Deas; H. Upadhyaya; S. Thomas. Psychiatry, Medical University of S.Carolina, Charleston, SC, USA. Co-occurring psychiatric disorders in adolescents with substance abuse is common. While many studies have explored the prevalence of psychiatric disorders in adolescent substance using samples, few have explored the relationship between comorbid psychiatric disorders and drinking behaviors in adolescents.
L. Sher1, 2; M. S. Milak1, 2; R. V. Parsey1, 2; T. B. Cooper1, 3; J. J. Carballo 1, 2; M. A. Oquendo1, 2; J. J. Mann1, 2 1. Department of Psychiatry, Columbia University, New York, NY, USA. 2. Department of Neuroscience, New York State Psychiatric Institute, New York, NY, USA. 3. Nathan Kline Institute […]
J. I. Nurnberger1, 4; R. Wiegand1; L. Bierut2; K. Bucholz2; T. Foroud4, 1; H. Edenberg3, 4; E. T. Meyer1; J. Kramer5; D. Dick2; W. Reich2; S. Kuperman5; V. Hesselbrock7; A. Goate2; B. Porjesz6; H. Begleiter61. Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA. 2. Psychiatry, Washington University School of Medicine, St. Louis, MO, USA. […]
T. E. Thiele1, 4; M. Navarro4; I. Cubero5; D. J. Knapp2, 4; G. R. Breese3, 4 1. Psychology, University of North Carolina, Chapel Hill, NC, USA. 2. Psychiatry, University of North Carolina, Chapel Hill, NC, USA. 3. Pharmacology, University of North Carolina, Chapel Hill, NC, USA. 4. Bowles Center for Alcohol Studies, University of North […]
J. M. Littleton. Kentucky Tobacco Research & Development Center, University of Kentucky, Lexington, KY, USA. Effective medications for drug and alcohol dependence are greatly needed, but progress has been slow. One problem is that, although several molecular targets can be identified, many of these present specific difficulties. For example it is quite clear that nicotinic […]
Haynes JC, Farrell M, Singleton N, Meltzer H, Araya R, Lewis G, Wiles NJ. Br J Psychiatry. 2005 Dec;187:544-51. BACKGROUND: Longitudinal studies have been inconclusive in identifying alcohol as a risk factor for anxiety and depression. AIMS: To examine whether excessive alcohol consumption is a risk factor for anxiety and depression in the general population, […]
Deardorff J, Gonzales NA, Christopher FS, Roosa MW, Millsap RE. Pediatrics. 2005 Dec;116(6):1451-6. OBJECTIVE: Early pubertal timing predicts deleterious outcomes for young girls, including substance use, risky sexual behavior, and pregnancy. In turn, adolescent pregnancy predicts long-term negative consequences such as reduced educational attainment and income-earning potential. Despite evidence of the direct links between early […]
Thom B. Am J Addict. 2005 Oct-Dec;14(5):416-25. With the publication of the Alcohol Harm Reduction Strategy for England in 2004,(1) it is timely to reflect on the social and political contexts that have influenced alcohol policy. This paper provides an overview of trends in the development of alcohol policy in England since 1950 with a […]
Hines LM, Ray L, Hutchison K, Tabakoff B. Dialogues Clin Neurosci. 2005;7(2):153-63. Alcohol dependence (alcoholism) is a complex disorder attributed to the interaction of genetic and environmental factors that form a collage of “disease” predisposition, which is not identical for every alcohol-dependent individual. There is considerable evidence to demonstrate that genetic predisposition accounts for roughly […]
