Topics

Obesity and its relationship to addictions: is overeating a form of addictive behavior?

Barry D, Clarke M, Petry NM.University of Connecticut Health Center, Farmington, Connecticut, USA.Am J Addict. 2009 Nov-Dec;18(6):439-51. Obesity is a major public health problem and notoriously difficult to treat. There are many parallels between obesity/overeating and addictions to alcohol and drugs. This paper discusses similarities between obesity and addictive disorders, including common personality characteristics, disruptive […]

What is this thing called “SAD”? A critique of the concept of Seasonal Affective Disorder

Hansen V, Skre I, Lund E.Institute of Clinical Medicine, University of Tromsø, Norway.Epidemiol Psichiatr Soc. 2008 Apr-Jun;17(2):120-7. BACKGROUND: Seasonal Affective Disorder (SAD) is supposed to be caused by lack of daylight in winter. Yet the population of Northern Norway, living without sun for two winter months, does not spontaneously complain about depression during the dark […]

Controlled trial of naturalistic dawn simulation and negative air ionization for seasonal affective disorder

Terman M, Terman JS.Department of Biopsychology, New York State Psychiatric Institute, New York, NY, USA.Am J Psychiatry. 2006 Dec;163(12):2126-33. OBJECTIVE: This trial assessed two novel nonpharmaceutical treatments for winter depression-naturalistic dawn simulation and high-density negative air ionization-delivered during the final hours of sleep. METHOD: The patients were 99 adults (77 women and 22 men) with […]

The role of genetic factors in the etiology of seasonal affective disorder and seasonality

Sher L, Goldman D, Ozaki N, Rosenthal NE.Clinical Psychobiology Branch, National Institute of Mental Health, Bethesda, MD, USA.J Affect Disord. 1999 Jun;53(3):203-10. The study of the genetic basis of seasonal affective disorder (SAD), a condition where depressions in fall and winter alternate with nondepressed periods in the spring and summer, has recently received attention. The […]

Effect of acute alcohol use on the lethality of suicide attempts in patients with mood disorders.

Sher L, Oquendo MA, Richardson-Vejlgaard R, Makhija NM, Posner K, Mann JJ, Stanley BH.Department of Psychiatry, Division of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, Columbia University, New York, NY, USA.J Psychiatr Res. 2009 Jul;43(10):901-5. Acute alcohol use is an important risk factor for attempted and completed suicide. We evaluated the effect of […]

A pilot study on differences in aggression in New York City and Madrid, Spain, and their possible impact on suicidal behavior

Baca-García E, Oquendo MA, Saiz-Ruiz J, Mann JJ, de Leon J.Department of Psychiatry, Fundación Jiménez Diaz, Madrid, Spain.J Clin Psychiatry. 2006 Mar;67(3):375-80. OBJECTIVE: Published results from a U.S. study of depressed suicide attempters and a Madrid, Spain, study including all consecutively admitted suicide attempters suggested that aggression scores were higher in U.S. attempters. This observation […]

A circadian signal of change of season in patients with seasonal affective disorder

Wehr TA, Duncan WC Jr, Sher L, Aeschbach D, Schwartz PJ, Turner EH, Postolache TT, Rosenthal NE. Section on Biological Rhythms, Mood and Anxiety Disorders Program, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892-1390, USA. Arch Gen Psychiatry. 2001 Dec;58(12):1108-14. BACKGROUND: In animals, the circadian pacemaker regulates seasonal […]

Association between seasonal affective disorder and the 5-HT2A promoter polymorphism, -1438G/A

Enoch MA, Goldman D, Barnett R, Sher L, Mazzanti CM, Rosenthal NE. Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA. Mol Psychiatry. 1999 Jan;4(1):89-92. Genes involved in serotonin metabolism are good candidates for the pathogenesis of seasonal affective disorder (SAD). A functional variant in the […]

The Can-SAD study: a randomized controlled trial of the effectiveness of light therapy and fluoxetine in patients with winter seasonal affective disorder

Lam RW, Levitt AJ, Levitan RD, Enns MW, Morehouse R, Michalak EE, Tam EM. Mood Disorders Centre, UBC Hospital, 2255 Wesbrook Mall, Vancouver, BC V6T 2A1. Am J Psychiatry. 2006 May;163(5):805-12. OBJECTIVE: Light therapy and antidepressants have shown comparable efficacy in separate studies of seasonal affective disorder treatment, but few studies have directly compared the […]

A birth-season/DRD4 gene interaction predicts weight gain and obesity in women with seasonal affective disorder: A seasonal thrifty phenotype hypothesis

Levitan RD, Masellis M, Lam RW, Kaplan AS, Davis C, Tharmalingam S, Mackenzie B, Basile VS, Kennedy JL. Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, ON, Canada. Neuropsychopharmacology. 2006 Nov;31(11):2498-503. We have recently described an association between the hypofunctional 7-repeat allele (7R) of the dopamine-4 receptor gene (DRD4), weight […]

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