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Differential Glucocorticoid Receptor Exon 1(B), 1(C), and 1(H) Expression and Methylation in Suicide Completers with a History of Childhood Abuse

Labonte B, Yerko V, Gross J, Mechawar N, Meaney MJ, Szyf M, Turecki G.Biol Psychiatry. 2012 Mar 21. [Epub ahead of print] AbstractBACKGROUND: Childhood abuse alters hypothalamic-pituitary-adrenal (HPA) function and increases the risk of suicide. Hippocampal glucocorticoid receptor (GR) activation regulates HPA activity, and human GR expression (hGR) is reduced in the hippocampus of suicide […]

Glucocorticoid-induced loss of DNA methylation in non-neuronal cells and potential involvement of DNMT1 in epigenetic regulation of Fkbp5

Yang X, Ewald ER, Huo Y, Tamashiro KL, Salvatori R, Sawa A, Wand GS, Lee RS.Biochem Biophys Res Commun. 2012 Mar 16. [Epub ahead of print] AbstractGlucocorticoids may play a significant role in the etiology of neuropsychiatric illnesses. Abnormalities in plasma cortisol levels, glucocorticoid sensitivity, and HPA-axis function often accompany clinical symptoms of stress-related illnesses […]

Controlled trial of safety and efficacy of bright light therapy vs. negative air ions in patients with bipolar depression

Dauphinais DR, Rosenthal JZ, Terman M, Difebo HM, Tuggle C, Rosenthal NE.Psychiatry Res. 2012 Mar 14. [Epub ahead of print] AbstractTreatment of bipolar disorder often results in patients taking several drugs in attempt to alleviate residual depressive symptoms, which can lead to an accumulation of side effects. New treatments for bipolar depression that do not […]

Sexual violence by occupational forces during and after World War II: influence of experiencing and witnessing of sexual violence on current mental health in a sample of elderly Austrians

Lueger-Schuster B, Glück TM, Tran US, Zeilinger EL.Int Psychogeriatr. 2012 Mar 21:1-5. [Epub ahead of print] AbstractBackground: Wartime rape is an atrocity with long-lasting impacts not only on victims but whole societies. In this brief report, we present data on experience and witness of sexual violence during World War II (WWII) and subsequent time of […]

Homicide victims in the military: 1980-1992

Helmkamp JC.Mil Med. 1995 Feb;160(2):51-6. AbstractData abstracted from the Report of Casualty (DD 1300) is used to describe active duty homicide victims for the period 1980 through 1992. The Marine Corps experienced the fewest homicides (186) but the highest rate (7.36 per 100,000) compared to the other services: Army (619/6.36), Navy (381/5.24), and Air Force […]

Suicide Among Veterans in 16 States, 2005 to 2008

Suicide Among Veterans in 16 States, 2005 to 2008: Comparisons Between Utilizers and Nonutilizers of Veterans Health Administration (VHA) Services Based on Data From the National Death Index, the National Violent Death Reporting System, and VHA Administrative Records. Katz IR, McCarthy JF, Ignacio RV, Kemp J.Am J Public Health. 2012 Mar;102 Suppl 1:S105-10. AbstractObjectives. We […]

Homicide by direct snake bite: a case of contract killing

Ambade VN, Borkar JL, Meshram SK.Med Sci Law. 2012 Jan;52(1):40-3. AbstractIt has been estimated that five million snake bite cases occur worldwide every year, causing about 100,000 deaths. Snake bite is exclusively accidental in nature. Suicide by snake bite is very rare and homicidal snake bite is not reported. In the present case, a contract […]

Symptom overlap in posttraumatic stress disorder and major depression

Gros DF, Price M, Magruder KM, Frueh BC.Psychiatry Res. 2012 Mar 2. [Epub ahead of print] AbstractOver the past decade there has been consistent criticism of the diagnostic criteria of posttraumatic stress disorder (PTSD) because of its high comorbidity with other mental disorders. Part of the problem surrounding PTSD may be related to the heterogeneity […]

Mental health consequences of the Chernobyl disaster

Bromet EJ.J Radiol Prot. 2012 Mar;32(1):N71-5. AbstractThe psychosocial consequences of disasters have been studied for more than 100 years. The most common mental health consequences are depression, anxiety, post-traumatic stress disorder, medically unexplained somatic symptoms, and stigma. The excess morbidity rate of psychiatric disorders in the first year after a disaster is in the order […]

Oxidative stress markers in patients with post-traumatic stress disorder

Ceprnja M, Derek L, Unic A, Blazev M, Fistonic M, Kozaric-Kovacic D, Franic M, Romic Z.Coll Antropol. 2011 Dec;35(4):1155-60 AbstractRecent study data support the role of oxidative stress in diverse psychiatric disorders. Oxidative stress results from an oxidant/antioxidant imbalance, an excess of oxidants and/or a depletion of antioxidants. There are numerous studies that indicate that […]

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