Golier JA, Caramanica K, Demaria R, Yehuda R.Depress Res Treat. 2012:393251. AbstractBackground. We obtained pilot data to examine the clinical and neuroendocrine effects of short-term mifepristone treatment in male veterans with PTSD. Methods. Eight male veterans with military-related PTSD completed a randomized, double-blind trial of one week of treatment with mifepristone (600 mg/day) or placebo. […]
Vermetten E, Lanius RA.Handb Clin Neurol. 2012;106:291-342. AbstractThree decades of posttraumatic stress disorder (PTSD) research have placed it well on the map. PTSD is a young disorder that started being properly understood only from 1980 with incorporation in DSM-III, in which it was acknowledged that exposure to traumatic events can lead to long-term psychopathology. This […]
Norredam M, Olsbjerg M, Petersen JH, Laursen B, Krasnik A.Inj Prev. 2012 May 24. [Epub ahead of print] AbstractBackground. The authors studied injury mortality in Denmark among refugees and immigrants compared with that among native Danes. Method. A register-based, historical prospective cohort design. All refugees (n=29,139) and family reunited immigrants (n=27,134) who between 1 January […]
Charlier P, Watier L, Ménétrier M, Chaillot PF, Brun L, Grandmaison GL.Med Hypotheses. 2012 May 22. [Epub ahead of print] AbstractDisturbances in some endocrine hormones have been implicated in the pathophysiology of depression and psychosis. We consider here further the hypothesis that there may be a correlation between suicide risk and the weight of the […]
Waters DD.Can J Cardiol. 2012 May 22. [Epub ahead of print] AbstractBiomarkers and imaging trials have often been used as guideposts in the development of drugs for atherosclerosis. This article explores the role of biomarkers and imaging trials in the development of 4 drugs: rimonabant, torcetrapib, ezetimibe, and niacin. Rimonabant, a selective cannabinoid-1 receptor, causes […]
Sperling W, Kreil S, Biermann T.J Nerv Ment Dis. 2012 May;200(5):423-8. ABSTRACT: The incidence of mental and somatic sequelae has been shown to be very high in people who survived the Holocaust. In the current study, 80 Holocaust survivors with posttraumatic stress disorder were examined based on evaluation of their complete record (medical reports, clinical […]
Nazarian D, Kimerling R, Frayne SM.J Trauma Stress. 2012 Apr;25(2):220-5. AbstractEvidence suggests that posttraumatic stress disorder (PTSD) and substance use disorders (SUD) are associated with poorer physical health among U.S. veterans who served in Operation Enduring Freedom and Operation Iraqi Freedom (OEF/OIF). No research of which we are aware has examined the independent and interactive […]
Rosenbluth M, Macqueen G, McIntyre RS, Beaulieu S, Schaffer A; Canadian Network for Mood and Anxiety Treatments (CANMAT) Task Force.Ann Clin Psychiatry. 2012 Feb;24(1):56-68. AbstractBACKGROUND: The association between mood disorders and personality disorders (PDs) is complicated clinically, conceptually, and neurobiologically. There is a need for recommendations to assist clinicians in treating these frequently encountered patients. […]
Letzter-Pouw S, Werner P.Am J Orthopsychiatry. 2012 Apr;82(2):201-8 AbstractThe prevalence of intrusive memories of the Holocaust and their relationship to distress was examined among 272 child survivors in Israel. Using attachment theory as a conceptual framework, the authors also examined the effects of type of experience and loss of parents in the Holocaust, psychological resources, […]
Johns DG, Duffy J, Fisher T, Hubbard BK, Forrest MJ.Drugs. 2012 Mar 5;72(4):491-507. AbstractLowering of serum low-density lipoprotein cholesterol (LDL-C) levels remains the primary aim of lipid management. Much progress has been made in reducing rates of cardiovascular disease morbidity and mortality, largely through increased awareness of lipid-lowering therapies and particularly through the use of […]
