Biomedical science is the application of biology-based science to medical use
Savas JN, Ribeiro LF, Wierda KD, Wright R, DeNardo-Wilke LA, Rice HC, Chamma I, Wang YZ, Zemla R, Lavallée-Adam M, Vennekens KM, O’Sullivan ML, Antonios JK, Hall EA, Thoumine O, Attie AD, Yates JR 3rd, Ghosh A, de Wit J.Neuron. 2015 Aug 19;87(4):764-80. Abstract. The formation, function, and plasticity of synapses require dynamic changes in […]
Elder G, Dorr NP, De Gasperi R, Gama Sosa MA, Shaughness MC, Maudlin-Jeronimo E, Hall AA, McCarron RM, Ahlers ST.J Neurotrauma. 2012 Nov 1;29(16):2564-75. Blast related traumatic brain injury (TBI) has been a major cause of injury in the wars in Iraq and Afghanistan. A striking feature of the mild TBI cases has been the […]
Guha S, Rosenfeld JA, Malhotra AK, Lee AT, Gregersen PK, Kane JM, Pe’er I, Darvasi A, Lencz T.Genome Biol. 2012 Jan 25;13(1):R2. Abstract. BACKGROUND: Relatively small, reproductively isolated populations with reduced genetic diversity may have advantages for genomewide association mapping in disease genetics. The Ashkenazi Jewish population represents a unique population for study based on […]
El-Sayed AM, Halossim MR, Galea S, Koenen KC.Biol Mood Anxiety Disord. 2012 Jun 14;2(1):10. [Epub ahead of print] AbstractABSTRACT: Epigenetic modifications are those reversible, mitotically heritable alterations in genomic expression that occur independent of changes in gene sequence. Epigenetic studies have the potential to improve our understanding of the etiology of mood and anxiety disorders […]
Zhang N, Zhao L, Ma S, Gu M, Zheng X.Int J Mol Med. 2012 Jun 14. doi: 10.3892/ijmm.2012.1033. [Epub ahead of print] AbstractIn contrast to other enzymes, Drosophila melanogaster deoxyribonucleoside kinase (Dm-dNK) has a broad substrate specificity and high catalytic rate when transferred in human cells. This makes it a promising therapeutic agent when administered […]
Philbert J, Pichat P, Palme R, Belzung C, Griebel G.Pharmacol Biochem Behav. 2012 May 31. [Epub ahead of print] Abstract. The selective antagonist at the CRF(1) receptor, SSR125543, has been shown to produce anxiolytic-like effects in a number of animal models. The aim of the present study was to verify whether these effects are mediated […]
Bangasser DA, Valentino RJ.Cell Mol Neurobiol. 2012 Apr 10. [Epub ahead of print] AbstractWomen are twice as likely as men to suffer from stress-related psychiatric disorders, like unipolar depression and post-traumatic stress disorder. Although the underlying neural mechanisms are not well characterized, the pivotal role of stress in the onset and severity of these diseases […]
A GFP-lacZ Bicistronic Reporter System for Promoter Analysis in Environmental Gram-Negative BacteriaSilva-Rocha R, de Lorenzo V.PLoS One. 2012;7(4):e34675. AbstractHere, we describe a bicistronic reporter system for the analysis of promoter activity in a variety of Gram-negative bacteria at both the population and single-cell levels. This synthetic genetic tool utilizes an artificial operon comprising the gfp […]
Carvajal-Carmona LG, Soto ID, Pineda N, Ortíz-Barrientos D, Duque C, Ospina-Duque J, McCarthy M, Montoya P, Alvarez VM, Bedoya G, Ruiz-Linares A.Am J Hum Genet. 2000 Nov;67(5):1287-95. Historical and genetic evidences suggest that the recently founded population of Antioquia (Colombia) is potentially useful for the genetic mapping of complex traits. This population was established in […]
Yang X, Ewald ER, Huo Y, Tamashiro KL, Salvatori R, Sawa A, Wand GS, Lee RS.Biochem Biophys Res Commun. 2012 Mar 16. [Epub ahead of print] AbstractGlucocorticoids may play a significant role in the etiology of neuropsychiatric illnesses. Abnormalities in plasma cortisol levels, glucocorticoid sensitivity, and HPA-axis function often accompany clinical symptoms of stress-related illnesses […]
