This section is dedicated to psychiatric, medical, and social problems associated with alcohol and drug abuse
Mameli M, Zamudio PA, Carta M, Valenzuela CF. J Neurosci. 2005 Aug 31;25(35):8027-36. Ethanol exposure during fetal development is a leading cause of learning disabilities. Studies suggest that it alters learning and memory by permanently damaging the hippocampus. It is generally assumed that this is mediated, in part, via alterations in glutamatergic transmission. Although NMDA […]
Koposov RA, Ruchkin VV, Eisemann M, Sidorov PI. Eur Child Adolesc Psychiatry. 2005 Aug;14(5):254-61. INTRODUCTION: Adolescent delinquency and alcohol abuse have become a growing concern in Russia. Psychopathology, a dysfunctional family and specific personality factors have all been linked to addictive and antisocial behavior. Since delinquent youth represent a specific risk group, where alcohol misuse […]
Simons JS, Oliver MN, Gaher RM, Ebel G, Brummels P. Addict Behav. 2005 Aug;30(7):1370-81. The present study examined associations between impulsivity and affect lability and methamphetamine and alcohol abuse and dependence symptoms in a rural inpatient treatment population (N=235). Thirty-two percent of participants reported methamphetamine use in the past 90 days prior to admission. Amphetamine […]
McKowen JW, Frye MA, Altshuler LL, Gitlin MJ. Bipolar Disord. 2005 Aug;7(4):377-81. OBJECTIVES: Despite a high prevalence rate, patients with bipolar disorder and active alcohol use are routinely excluded from controlled clinical trials leaving clinicians with little evidence-based medicine to guide treatment. This report evaluates preliminary data of alcohol consumption patterns utilizing the Alcohol Timeline […]
Strakowski SM, DelBello MP, Fleck DE, Adler CM, Anthenelli RM, Keck PE Jr, Arnold LM, Amicone J. Arch Gen Psychiatry. 2005 Aug;62(8):851-8. CONTEXT: Alcohol-use disorders are common co-occurring conditions affecting bipolar patients, and this co-occurrence is negatively associated with outcome. OBJECTIVE: The primary goal of this study was to identify how the relative onsets of […]
Vinod KY, Hungund BL. Life Sci. 2005 Aug 19;77(14):1569-83. Several natural lipids have emerged as candidate modulators of central nervous system (CNS) functions. Fatty acid amides and their coupled signaling pathways are known to regulate several physiological and behavioral processes. Recent studies from our laboratory and others also have implicated endogenous marijuana-like brain constituents, endocannabinoids […]
Choi IG, Son HG, Yang BH, Kim SH, Lee JS, Chai YG, Son BK, Kee BS, Park BL, Kim LH, Choi YH, Shin HD. Hum Mutat. 2005 Sep;26(3):224-34. Alcoholism is a multifactorial and polygenic disorder involving complex gene-to-gene and gene-to-environment interactions. Alcohol metabolism is one of the biological determinants that could significantly be influenced by […]
Curtis D, Knight J, Sham PC. Psychiatr Genet. 2005 Sep;15(3):181-187 OBJECTIVE: Although LOD score methods have been applied to diseases with complex modes of inheritance, linkage analysis of quantitative traits has tended to rely on non-parametric methods based on regression or variance components analysis. Here, we describe a new method for LOD score analysis of […]
Kohnke MD, Batra A, Kolb W, Kohnke AM, Lutz U, Schick S, Gaertner I. Alcohol Alcohol. 2005 Sep-Oct;40(5):339-42. AIMS: It was investigated whether the allele A9 of the dopamine transporter gene (DAT1; SLC6A3) is associated with alcoholism, delirium tremens (DT), alcohol withdrawal seizures (AWS), or the daily alcohol intake.
Kiefer F, Jahn H, Otte C, Demiralay C, Wolf K, Wiedemann K. J Psychiatr Res. 2005 Sep;39(5):545-551. The appetite regulating peptide leptin has recently been associated with craving for alcohol and lifetime ethanol intake. However, effects of anti- craving drugs on leptin have not been studied until now.
