Leo Sher, M.D. A review article, “The role of inflammation in the pathophysiology of depression and suicidal behavior: Implications for treatment” was published in the January 2023 issue of Medical Clinics of North America (1). Depression and suicidal behavior are complex psychiatric conditions of significant public health concerns due to their debilitating nature. The need […]
Leo Sher, M.D. On December 19, 2024, the U.S. Department of Veterans Affairs released the “2024 National Veteran Suicide Prevention Annual Report.” The Annual Report consists of two parts: “In-depth Reviews” (1) and “Report Findings” (2). The Report suggests that in 2022, there were 6,407 suicides among Veterans and 41,484 among non-Veteran U.S. adults. Among […]
Leo Sher, M.D. Our research report, “The number of previous depressive episodes is positively associated with cortisol response to fenfluramine administration” was published 20 years ago in December 2004 in the Annals of the New York Academy of Sciences (1). Multiple reports document hypothalamic-pituitary-axis (HPA) hyperactivity in depressed patients. Measurement of cortisol levels after ingestion […]
Leo Sher, M.D. Our research work, “Free thyroxine and thyroid-stimulating hormone levels in patients with seasonal affective disorder and matched controls” was published 25 years ago in the December 1999 issue of the Journal of Affective Disorders (1). Some symptoms of seasonal affective disorder (SAD), such as decreased energy and weight gain, also occur in […]
Leo Sher, M.D. A research report, “Traumatic brain injury in U.S. veterans: Prevalence and associations with physical, mental, and cognitive health” has been published in Archives of Physical Medicine and Rehabilitation online ahead of print (1). The authors examined the prevalence of traumatic brain injury (TBI) in the U.S. veteran population, and physical, mental, and […]
Leo Sher, M.D. Our review article, “International trends in male youth suicide and suicidal behavior” has been published in Acta Neuropsychiatrica (1). To our knowledge, our article is the most comprehensive review of global developments in male youth suicidal behavior in the world literature. A summary of our review paper, “International trends in male youth […]
Leo Sher, M.D. My review article, “The impact of relationships within combat units on post-deployment suicide risk” has been published in Behavioral Sciences (1). This is the first review of the relation between interactions within combat entities and post-deployment suicidality in world literature. A summary of my review is below: “Multiple deployment factors may affect […]
Leo Sher, M.D. A research paper, “Bright light therapy for nonseasonal depressive disorders: A systematic review and meta-analysis” has been published in JAMA Psychiatry online ahead of print (1). Researchers from Brazil performed a search of publications in the MEDLINE, Embase, and Cochrane databases for randomized clinical trials evaluating bright light therapy effects in patients […]
Leo Sher, M.D. Our research report, “Objections to suicide among depressed patients with alcohol use disorders” was published 15 years ago in the October 2009 issue of the Journal of Affective Disorders (1). In all, 521 mood disordered patients with and without alcohol use disorders were administered a battery of clinical measures including the Scale […]
Leo Sher, M.D. A research report, “A false sense of security: Rapid improvement as a red flag for death by suicide” was published in 2022 in the Journal of Consulting and Clinical Psychology (1). Postdischarge from inpatient psychiatry is the highest risk period for suicide. The majority of deaths by suicide postdischarge happened within the […]
